Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death

Autophagy is a catabolic mechanism facilitating degradation of cytoplasmic proteins and organelles in a lysosome-dependent manner. Autophagy flux is necessary for normal neuronal homeostasis and its dysfunction contributes to neuronal cell death in several neurodegenerative diseases. Elevated autoph...

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Detalles Bibliográficos
Autores principales: Liu, S, Sarkar, C, Dinizo, M, Faden, A I, Koh, E Y, Lipinski, M M, Wu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669738/
https://www.ncbi.nlm.nih.gov/pubmed/25569099
http://dx.doi.org/10.1038/cddis.2014.527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669738/
https://www.ncbi.nlm.nih.gov/pubmed/25569099
http://dx.doi.org/10.1038/cddis.2014.527

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