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Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic pathway. Here we demonstrate that ER stress can also induce necroptosis, an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669746/ https://www.ncbi.nlm.nih.gov/pubmed/25569104 http://dx.doi.org/10.1038/cddis.2014.548 |