Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

Endoplasmic reticulum (ER) stress-induced cellular dysfunction and death is associated with several human diseases. It has been widely reported that ER stress kills through activation of the intrinsic mitochondrial apoptotic pathway. Here we demonstrate that ER stress can also induce necroptosis, an...

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Detalles Bibliográficos
Autores principales: Saveljeva, S, Mc Laughlin, S L, Vandenabeele, P, Samali, A, Bertrand, M J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669746/
https://www.ncbi.nlm.nih.gov/pubmed/25569104
http://dx.doi.org/10.1038/cddis.2014.548

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