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Bmi1 regulates auditory hair cell survival by maintaining redox balance

Reactive oxygen species (ROS) accumulation are involved in noise- and ototoxic drug-induced hair cell loss, which is the major cause of hearing loss. Bmi1 is a member of the Polycomb protein family and has been reported to regulate mitochondrial function and ROS level in thymocytes and neurons. In t...

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Detalles Bibliográficos
Autores principales: Chen, Y, Li, L, Ni, W, Zhang, Y, Sun, S, Miao, D, Chai, R, Li, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669747/
https://www.ncbi.nlm.nih.gov/pubmed/25611380
http://dx.doi.org/10.1038/cddis.2014.549