Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress

Phosphorylation of the α subunit of the translation initiation factor eIF2 at serine 51 (eIF2αP) is a master regulator of cell adaptation to various forms of stress with implications in antitumor treatments with chemotherapeutic drugs. Herein, we demonstrate that genetic loss of the eIF2α kinases PE...

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Detalles Bibliográficos
Autores principales: Rajesh, K, Krishnamoorthy, J, Kazimierczak, U, Tenkerian, C, Papadakis, A I, Wang, S, Huang, S, Koromilas, A E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669752/
https://www.ncbi.nlm.nih.gov/pubmed/25590801
http://dx.doi.org/10.1038/cddis.2014.554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669752/
https://www.ncbi.nlm.nih.gov/pubmed/25590801
http://dx.doi.org/10.1038/cddis.2014.554

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