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Intracellular annexin A2 regulates NF-κB signaling by binding to the p50 subunit: implications for gemcitabine resistance in pancreatic cancer

Annexin A2 (ANXA2) expression is highly upregulated in many types of cancer. Although cell surface localization of ANXA2 has been reported to have a critical role in the progression and metastasis of a variety of tumors, including pancreatic cancer, the biological role of intracellular ANXA2 is not...

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Detalles Bibliográficos
Autores principales: Jung, H, Kim, J S, Kim, W K, Oh, K-J, Kim, J-M, Lee, H J, Han, B S, Kim, D S, Seo, Y S, Lee, S C, Park, S G, Bae, K-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669756/
https://www.ncbi.nlm.nih.gov/pubmed/25611381
http://dx.doi.org/10.1038/cddis.2014.558