Cargando…
Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice
Primary ovarian insufficiency (POI) is a common cause of infertility in around 1–2% of women aged <40 years. However, the mechanisms that cause POI are still poorly understood. Here we showed that germ cell-specific knockout of an essential autophagy induction gene Atg7 led to subfertility in fem...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669757/ https://www.ncbi.nlm.nih.gov/pubmed/25590799 http://dx.doi.org/10.1038/cddis.2014.559 |