Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

Primary ovarian insufficiency (POI) is a common cause of infertility in around 1–2% of women aged <40 years. However, the mechanisms that cause POI are still poorly understood. Here we showed that germ cell-specific knockout of an essential autophagy induction gene Atg7 led to subfertility in fem...

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Detalles Bibliográficos
Autores principales: Song, Z-H, Yu, H-Y, Wang, P, Mao, G-K, Liu, W-X, Li, M-N, Wang, H-N, Shang, Y-L, Liu, C, Xu, Z-L, Sun, Q-Y, Li, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669757/
https://www.ncbi.nlm.nih.gov/pubmed/25590799
http://dx.doi.org/10.1038/cddis.2014.559

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