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The role of hypoxia-inducible factor-2 in digestive system cancers

Hypoxia is an all but ubiquitous phenomenon in cancers. Two known hypoxia-inducible factors (HIFs), HIF-1α and HIF-2α, primarily mediate the transcriptional response to hypoxia. Despite the high homology between HIF-1α and HIF-2α, emerging evidence suggests differences between both molecules in term...

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Detalles Bibliográficos
Autores principales: Zhao, J, Du, F, Shen, G, Zheng, F, Xu, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669763/
https://www.ncbi.nlm.nih.gov/pubmed/25590810
http://dx.doi.org/10.1038/cddis.2014.565