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Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice
Ageing is a complex biological process for which underlying biochemical changes are still largely unknown. We performed comparative profiling of the cellular proteome and metabolome to understand the molecular basis of ageing in Caspase-2-deficient (Casp2(−/−)) mice that are a model of premature age...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669765/ https://www.ncbi.nlm.nih.gov/pubmed/25611376 http://dx.doi.org/10.1038/cddis.2014.567 |