Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

Ageing is a complex biological process for which underlying biochemical changes are still largely unknown. We performed comparative profiling of the cellular proteome and metabolome to understand the molecular basis of ageing in Caspase-2-deficient (Casp2(−/−)) mice that are a model of premature age...

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Detalles Bibliográficos
Autores principales: Wilson, C H, Shalini, S, Filipovska, A, Richman, T R, Davies, S, Martin, S D, McGee, S L, Puccini, J, Nikolic, A, Dorstyn, L, Kumar, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669765/
https://www.ncbi.nlm.nih.gov/pubmed/25611376
http://dx.doi.org/10.1038/cddis.2014.567

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