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The BH3-only protein Bad is dispensable for TNF-mediated cell death

Tumor necrosis factor (TNF) is a key signaling molecule orchestrating immune and inflammatory responses and possesses the capacity to trigger apoptotic as well as necroptotic cell death. Apoptotic cell death elicited by TNF has been demonstrated to engage pro-apoptotic Bcl-2 family proteins, most pr...

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Detalles Bibliográficos
Autores principales: Ottina, E, Sochalska, M, Sgonc, R, Villunger, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669773/
https://www.ncbi.nlm.nih.gov/pubmed/25611386
http://dx.doi.org/10.1038/cddis.2014.575