ING1b negatively regulates HIF1α protein levels in adipose-derived stromal cells by a SUMOylation-dependent mechanism

Hypoxic niches help maintain mesenchymal stromal cell properties, and their amplification under hypoxia sustains their immature state. However, how MSCs maintain their genomic integrity in this context remains elusive, since hypoxia may prevent proper DNA repair by downregulating expression of BRCA1...

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Detalles Bibliográficos
Autores principales: Bigot, N, Guérillon, C, Loisel, S, Bertheuil, N, Sensebé, L, Tarte, K, Pedeux, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669774/
https://www.ncbi.nlm.nih.gov/pubmed/25611387
http://dx.doi.org/10.1038/cddis.2014.577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669774/
https://www.ncbi.nlm.nih.gov/pubmed/25611387
http://dx.doi.org/10.1038/cddis.2014.577

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