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Loss of anchorage primarily induces non-apoptotic cell death in a human mammary epithelial cell line under atypical focal adhesion kinase signaling

Anchorage dependence of cellular growth and survival prevents inappropriate cell growth or survival in ectopic environments, and serves as a potential barrier to metastasis of cancer cells. Therefore, obtaining a better understanding of anchorage-dependent responses in normal cells is the first step...

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Detalles Bibliográficos
Autores principales: Ishikawa, F, Ushida, K, Mori, K, Shibanuma, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669778/
https://www.ncbi.nlm.nih.gov/pubmed/25611393
http://dx.doi.org/10.1038/cddis.2014.583