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CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4

Cancer cells rely on glycolysis to maintain high levels of anabolism. However, the metabolism of glucose via glycolysis in cancer cells is frequently incomplete and results in the accumulation of acidic metabolites such as pyruvate and lactate. Thus, the cells have to develop strategies to alleviate...

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Detalles Bibliográficos
Autores principales: Wang, L, Zhou, H, Wang, Y, Cui, G, Di, L-j
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669780/
https://www.ncbi.nlm.nih.gov/pubmed/25633289
http://dx.doi.org/10.1038/cddis.2014.587