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Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications

Mitogen-activated protein kinase kinase 3 (MAP2K3, MKK3) is a member of the dual specificity protein kinase group that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic or stress-inducing stimuli and participates in the MAP kinase-mediated signaling cascade, leading to c...

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Detalles Bibliográficos
Autores principales: Baldari, S, Ubertini, V, Garufi, A, D'Orazi, G, Bossi, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669782/
https://www.ncbi.nlm.nih.gov/pubmed/25633290
http://dx.doi.org/10.1038/cddis.2014.591