Cargando…
Targeting MKK3 as a novel anticancer strategy: molecular mechanisms and therapeutical implications
Mitogen-activated protein kinase kinase 3 (MAP2K3, MKK3) is a member of the dual specificity protein kinase group that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic or stress-inducing stimuli and participates in the MAP kinase-mediated signaling cascade, leading to c...
Autores principales: | Baldari, S, Ubertini, V, Garufi, A, D'Orazi, G, Bossi, G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669782/ https://www.ncbi.nlm.nih.gov/pubmed/25633290 http://dx.doi.org/10.1038/cddis.2014.591 |
Ejemplares similares
-
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
por: Pistritto, Giuseppa, et al.
Publicado: (2016) -
The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells
por: Garufi, Alessia, et al.
Publicado: (2015) -
Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences
por: Cirone, Mara, et al.
Publicado: (2019) -
Zn(II)-curc targets p53 in thyroid cancer cells
por: GARUFI, ALESSIA, et al.
Publicado: (2015) -
p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions
por: Garufi, Alessia, et al.
Publicado: (2017)