APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation

Amyloid precursor protein (APP) is best known for its involvement in the pathogenesis of Alzheimer's disease. We have previously demonstrated that APP intracellular domain (AICD) regulates neurogenesis; however, the mechanisms underlying AICD-mediated regulation of neuronal differentiation are...

Descripción completa

Detalles Bibliográficos
Autores principales: Shu, R, Wong, W, Ma, Q H, Yang, Z Z, Zhu, H, Liu, F J, Wang, P, Ma, J, Yan, S, Polo, J M, Bernard, C C A, Stanton, L W, Dawe, G S, Xiao, Z C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669786/
https://www.ncbi.nlm.nih.gov/pubmed/25695604
http://dx.doi.org/10.1038/cddis.2015.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669786/
https://www.ncbi.nlm.nih.gov/pubmed/25695604
http://dx.doi.org/10.1038/cddis.2015.10

Ejemplares similares