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Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth

Sonic hedgehog (Shh) functions as a conserved morphogen in the development of various organs in metazoans ranging from Drosophila to humans. Here, we have investigated the potential roles and underlying mechanisms of Shh signaling in murine placentation. Immunostaining revealed the abundant expressi...

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Detalles Bibliográficos
Autores principales: Pan, Y B, Gong, Y, Ruan, H F, Pan, L Y, Wu, X K, Tang, C, Wang, C J, Zhu, H B, Zhang, Z M, Tang, L F, Zou, C C, Wang, H B, Wu, X M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669788/
https://www.ncbi.nlm.nih.gov/pubmed/25695606
http://dx.doi.org/10.1038/cddis.2015.28