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Mitochondrial Lon regulates apoptosis through the association with Hsp60–mtHsp70 complex
Human Lon protease is a mitochondrial matrix protein with several functions, including protein degradation, mitochondrial DNA (mtDNA) binding, and chaperone activity. Lon is currently emerging as an important regulator of mitochondria-contributed tumorigenesis due to its overexpression in cancer cel...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669791/ https://www.ncbi.nlm.nih.gov/pubmed/25675302 http://dx.doi.org/10.1038/cddis.2015.9 |