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TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium

The intestinal mucosa undergoes a continual process of proliferation, differentiation and apoptosis, which is regulated by multiple signaling pathways. Notch signaling is critical for the control of intestinal stem cell maintenance and differentiation. However, the precise mechanisms involved in the...

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Detalles Bibliográficos
Autores principales: Zhou, Y, Rychahou, P, Wang, Q, Weiss, H L, Evers, B M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669793/
https://www.ncbi.nlm.nih.gov/pubmed/25654764
http://dx.doi.org/10.1038/cddis.2014.588