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TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium
The intestinal mucosa undergoes a continual process of proliferation, differentiation and apoptosis, which is regulated by multiple signaling pathways. Notch signaling is critical for the control of intestinal stem cell maintenance and differentiation. However, the precise mechanisms involved in the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669793/ https://www.ncbi.nlm.nih.gov/pubmed/25654764 http://dx.doi.org/10.1038/cddis.2014.588 |