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JNK pathway activation is able to synchronize neuronal death and glial phagocytosis in Drosophila

Glial phagocytosis of superfluous neurons and damaged or aberrant neuronal material is crucial for normal development and maintenance of the CNS. However, the molecular mechanisms underlying the relationship between neuronal death and glial phagocytosis are poorly understood. We describe a novel mec...

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Detalles Bibliográficos
Autores principales: Shklover, J, Mishnaevski, K, Levy-Adam, F, Kurant, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669801/
https://www.ncbi.nlm.nih.gov/pubmed/25695602
http://dx.doi.org/10.1038/cddis.2015.27