Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells

The Gram-negative bacterium Vibrio vulnificus produces hemolysin (VvhA), which induces cytotoxicity in mammalian cells. However, our understanding of the cytotoxic mechanism and the modes of action of VvhA are still fragmentary and incomplete. The recombinant protein (r) VvhA (50 pg/ml) significantl...

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Detalles Bibliográficos
Autores principales: Lee, S-J, Jung, Y H, Oh, S Y, Song, E J, Choi, S H, Han, H J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669806/
https://www.ncbi.nlm.nih.gov/pubmed/25695598
http://dx.doi.org/10.1038/cddis.2015.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669806/
https://www.ncbi.nlm.nih.gov/pubmed/25695598
http://dx.doi.org/10.1038/cddis.2015.19

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