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The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine
The NLR pyrin domain containing 3 (NLRP3) inflammasome is a major component of the innate immune system, but its mechanism of activation by a wide range of molecules remains largely unknown. Widely used nano-sized inorganic metal oxides such as silica dioxide (nano-SiO(2)) and titanium dioxide (nano...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669808/ https://www.ncbi.nlm.nih.gov/pubmed/25654762 http://dx.doi.org/10.1038/cddis.2014.576 |