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The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells

Nuclear factor of activated T cells 1 (NFAT1) expression has been associated with increased migratory/invasive properties of mammary tumor-derived cell lines in vitro. It is unknown, however, if NFAT activation actually occurs in breast cancer cases and whether the calcineurin/NFAT pathway is import...

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Detalles Bibliográficos
Autores principales: Tran Quang, C, Leboucher, S, Passaro, D, Fuhrmann, L, Nourieh, M, Vincent-Salomon, A, Ghysdael, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669815/
https://www.ncbi.nlm.nih.gov/pubmed/25719243
http://dx.doi.org/10.1038/cddis.2015.14