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Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion
TRAIL is involved in immune tumor surveillance and is considered a promising anti-cancer agent owing to its limited side effects on healthy cells. However, some cancer cells display resistance, or become resistant to TRAIL-induced cell death. Hyperthermia can enhance sensitivity to TRAIL-induced cel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669817/ https://www.ncbi.nlm.nih.gov/pubmed/25675293 http://dx.doi.org/10.1038/cddis.2015.12 |