Cargando…
Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion
TRAIL is involved in immune tumor surveillance and is considered a promising anti-cancer agent owing to its limited side effects on healthy cells. However, some cancer cells display resistance, or become resistant to TRAIL-induced cell death. Hyperthermia can enhance sensitivity to TRAIL-induced cel...
Autores principales: | Morlé, A, Garrido, C, Micheau, O |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669817/ https://www.ncbi.nlm.nih.gov/pubmed/25675293 http://dx.doi.org/10.1038/cddis.2015.12 |
Ejemplares similares
-
Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells
por: Iessi, Elisabetta, et al.
Publicado: (2015) -
Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells
por: Song, X, et al.
Publicado: (2013) -
c-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor–induced Apoptosis
por: Mathas, Stephan, et al.
Publicado: (2004) -
The heme oxygenase-1 and c-FLIP in acute myeloid leukemias: two non-redundant but mutually exclusive cellular safeguards protecting cells against TNF-induced cell death?
por: Shirley, S., et al.
Publicado: (2010) -
TRAIL-R4 Promotes Tumor Growth and Resistance to Apoptosis in Cervical Carcinoma HeLa Cells through AKT
por: Lalaoui, Najoua, et al.
Publicado: (2011)