Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death

The brains of patients with Alzheimer's disease (AD) present elevated levels of tumor necrosis factor-α (TNFα), a cytokine that has a dual function in neuronal cells. On one hand, TNFα can activate neuronal apoptosis, and on the other hand, it can protect these cells against amyloid-β (Aβ) toxi...

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Detalles Bibliográficos
Autores principales: Carriba, P, Jimenez, S, Navarro, V, Moreno-Gonzalez, I, Barneda-Zahonero, B, Moubarak, R S, Lopez-Soriano, J, Gutierrez, A, Vitorica, J, Comella, J X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669818/
https://www.ncbi.nlm.nih.gov/pubmed/25675299
http://dx.doi.org/10.1038/cddis.2015.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669818/
https://www.ncbi.nlm.nih.gov/pubmed/25675299
http://dx.doi.org/10.1038/cddis.2015.6

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