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Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain
Neurodegeneration is a serious issue of neurodegenerative diseases including epilepsy. Downregulation of the chloride transporter KCC2 in the epileptic tissue may not only affect regulation of the polarity of GABAergic synaptic transmission but also neuronal survival. Here, we addressed the mechanis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669822/ https://www.ncbi.nlm.nih.gov/pubmed/26043076 http://dx.doi.org/10.1038/cddis.2015.127 |