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Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain

Neurodegeneration is a serious issue of neurodegenerative diseases including epilepsy. Downregulation of the chloride transporter KCC2 in the epileptic tissue may not only affect regulation of the polarity of GABAergic synaptic transmission but also neuronal survival. Here, we addressed the mechanis...

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Detalles Bibliográficos
Autores principales: Winkelmann, A, Semtner, M, Meier, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669822/
https://www.ncbi.nlm.nih.gov/pubmed/26043076
http://dx.doi.org/10.1038/cddis.2015.127

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