Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation

While many anticancer therapies aim to target the death of tumor cells, sophisticated resistance mechanisms in the tumor cells prevent cell death induction. In particular enzymes of the glutathion-S-transferase (GST) family represent a well-known detoxification mechanism, which limit the effect of c...

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Detalles Bibliográficos
Autores principales: Brockmann, A, Bluwstein, A, Kögel, A, May, S, Marx, A, Tschan, M P, Brunner, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669824/
https://www.ncbi.nlm.nih.gov/pubmed/26043078
http://dx.doi.org/10.1038/cddis.2015.137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669824/
https://www.ncbi.nlm.nih.gov/pubmed/26043078
http://dx.doi.org/10.1038/cddis.2015.137

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