ICAM-1 suppresses tumor metastasis by inhibiting macrophage M2 polarization through blockade of efferocytosis

Efficient clearance of apoptotic cells (efferocytosis) can profoundly influence tumor-specific immunity. Tumor-associated macrophages are M2-polarized macrophages that promote key processes in tumor progression. Efferocytosis stimulates M2 macrophage polarization and contributes to cancer metastasis...

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Detalles Bibliográficos
Autores principales: Yang, M, Liu, J, Piao, C, Shao, J, Du, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669827/
https://www.ncbi.nlm.nih.gov/pubmed/26068788
http://dx.doi.org/10.1038/cddis.2015.144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669827/
https://www.ncbi.nlm.nih.gov/pubmed/26068788
http://dx.doi.org/10.1038/cddis.2015.144

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