Vibrio vulnificus VvpE inhibits mucin 2 expression by hypermethylation via lipid raft-mediated ROS signaling in intestinal epithelial cells

Mucin is an important physical barrier against enteric pathogens. VvpE is an elastase encoded by Gram-negative bacterium Vibrio vulnificus; however, the functional role of VvpE in intestinal mucin (Muc) production is yet to be elucidated. The recombinant protein (r) VvpE significantly reduced the le...

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Detalles Bibliográficos
Autores principales: Lee, S-J, Jung, Y H, Oh, S Y, Jang, K K, Lee, H S, Choi, S H, Han, H J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669833/
https://www.ncbi.nlm.nih.gov/pubmed/26086960
http://dx.doi.org/10.1038/cddis.2015.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669833/
https://www.ncbi.nlm.nih.gov/pubmed/26086960
http://dx.doi.org/10.1038/cddis.2015.152

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