Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3β-Snail pathway

Pancreatic cancer is one of the most difficult malignancies to treat owing to the rapid acquisition of resistance to chemotherapy. Gemcitabine, a first-line treatment for pancreatic cancer, prolongs patient survival by several months, and combination treatment with gemcitabine and other anti-cancer...

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Detalles Bibliográficos
Autores principales: Namba, T, Kodama, R, Moritomo, S, Hoshino, T, Mizushima, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669843/
https://www.ncbi.nlm.nih.gov/pubmed/26111057
http://dx.doi.org/10.1038/cddis.2015.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669843/
https://www.ncbi.nlm.nih.gov/pubmed/26111057
http://dx.doi.org/10.1038/cddis.2015.172

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