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Effects of Trichostatin A on drug uptake transporters in primary rat hepatocyte cultures

The present study was set up to investigate the effects of Trichostatin A (TSA), a prototypical epigenetic modifier, on the expression and activity of hepatic drug uptake transporters in primary cultured rat hepatocytes. To this end, the expression of the sinusoidal transporters sodium-dependent tau...

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Detalles Bibliográficos
Autores principales: Ramboer, Eva, Rogiers, Vera, Vanhaecke, Tamara, Vinken, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669911/
https://www.ncbi.nlm.nih.gov/pubmed/26648816
http://dx.doi.org/10.17179/excli2015-220