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Xiaokeping mixture inhibits diabetic nephropathy in streptozotocin-induced rats through blocking TGF-β1/Smad7 signaling

BACKGROUND: Diabetic nephropathy (DN) is a major cause of chronic kidney failure and characterized by excessive deposition of extracellular matrix. Evidence have shown that transforming growth factor-β1 (TGF-β1) is a key mediator in the development of DN. However, treatment of DN by blocking the TGF...

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Detalles Bibliográficos
Autores principales: Xin, Chuanwei, Xia, Zhongni, Jiang, Cheng, Lin, Mengmeng, Li, Gonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670018/
https://www.ncbi.nlm.nih.gov/pubmed/26664048
http://dx.doi.org/10.2147/DDDT.S93964