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Xiaokeping mixture inhibits diabetic nephropathy in streptozotocin-induced rats through blocking TGF-β1/Smad7 signaling

BACKGROUND: Diabetic nephropathy (DN) is a major cause of chronic kidney failure and characterized by excessive deposition of extracellular matrix. Evidence have shown that transforming growth factor-β1 (TGF-β1) is a key mediator in the development of DN. However, treatment of DN by blocking the TGF...

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Detalles Bibliográficos
Autores principales:	Xin, Chuanwei, Xia, Zhongni, Jiang, Cheng, Lin, Mengmeng, Li, Gonghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670018/ https://www.ncbi.nlm.nih.gov/pubmed/26664048 http://dx.doi.org/10.2147/DDDT.S93964

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