The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington’s Disease

Huntington’s disease (HD) is an autosomal-dominant neurodegenerative disorder resulting from expansion of CAG repeats in the Huntingtin (HTT) gene. Previous studies have shown mutant HTT can alter expression of genes associated with dysregulated epigenetic modifications. One of the most widely studi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Xianjun, Tsuji, Junko, Labadorf, Adam, Roussos, Panos, Chen, Jiang-Fan, Myers, Richard H., Akbarian, Schahram, Weng, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670094/
https://www.ncbi.nlm.nih.gov/pubmed/26636336
http://dx.doi.org/10.1371/journal.pone.0144398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670094/
https://www.ncbi.nlm.nih.gov/pubmed/26636336
http://dx.doi.org/10.1371/journal.pone.0144398

Ejemplares similares