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Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma

It has been hypothesized that synaptic pruning precedes retinal ganglion cell degeneration in glaucoma, causing early dysfunction to retinal ganglion cells. To begin to assess this, we studied the excitatory synaptic inputs to individual ganglion cells in normal mouse retinas and in retinas with gan...

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Detalles Bibliográficos
Autores principales: Berry, Ryan H., Qu, Juan, John, Simon W. M., Howell, Gareth R., Jakobs, Tatjana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670161/
https://www.ncbi.nlm.nih.gov/pubmed/26637126
http://dx.doi.org/10.1371/journal.pone.0144341