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The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model

Neurodegenerative diseases provoke robust immunological reactions in the central nervous system (CNS), which further deteriorate the neural tissue damage. We hypothesized that the expression levels of indoleamine 2,3-dioxygenase (IDO), an enzyme that has potent immune suppressive activities, in neur...

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Detalles Bibliográficos
Autores principales: Lee, Young Eun, An, Jaeyeol, Lee, Kee-Hang, Kim, Sung Su, Song, Hye Jin, Pyeon, Heejang, Nam, Hyun, Kang, Kyeongjin, Joo, Kyeung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670164/
https://www.ncbi.nlm.nih.gov/pubmed/26636969
http://dx.doi.org/10.1371/journal.pone.0144298