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Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

AIMS/HYPOTHESIS: Ageing can lead to reduced insulin sensitivity and loss of pancreatic beta cell function, predisposing individuals to the development of diabetes. The aim of this study was to assess the contribution of microRNAs (miRNAs) to age-associated beta cell dysfunction. METHODS: The global...

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Detalles Bibliográficos
Autores principales: Tugay, Ksenia, Guay, Claudiane, Marques, Ana C., Allagnat, Florent, Locke, Jonathan M., Harries, Lorna W., Rutter, Guy A., Regazzi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670458/
https://www.ncbi.nlm.nih.gov/pubmed/26474776
http://dx.doi.org/10.1007/s00125-015-3783-5