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Human IgG4: a structural perspective

IgG4, the least represented human IgG subclass in serum, is an intriguing antibody with unique biological properties, such as the ability to undergo Fab-arm exchange and limit immune complex formation. The lack of effector functions, such as antibody-dependent cell-mediated cytotoxicity and compleme...

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Detalles Bibliográficos
Autores principales: Davies, Anna M, Sutton, Brian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670484/
https://www.ncbi.nlm.nih.gov/pubmed/26497518
http://dx.doi.org/10.1111/imr.12349