Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1p(ΔNterm) only in combination with Ldb16p

BACKGROUND: Seipin is required for the correct assembly of cytoplasmic lipid droplets. In the absence of the yeast seipin homolog Sei1p (formerly Fld1p), droplets are slow to bud from the endoplasmic reticulum, lack the normal component of proteins on their surface, are highly heterogeneous in size...

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Detalles Bibliográficos
Autores principales: Han, Sungwon, Binns, Derk D., Chang, Yu-Fang, Goodman, Joel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670494/
https://www.ncbi.nlm.nih.gov/pubmed/26637296
http://dx.doi.org/10.1186/s12860-015-0075-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670494/
https://www.ncbi.nlm.nih.gov/pubmed/26637296
http://dx.doi.org/10.1186/s12860-015-0075-3

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