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Rare variants analysis using penalization methods for whole genome sequence data
BACKGROUND: Availability of affordable and accessible whole genome sequencing for biomedical applications poses a number of statistical challenges and opportunities, particularly related to the analysis of rare variants and sparseness of the data. Although efforts have been devoted to address these...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670502/ https://www.ncbi.nlm.nih.gov/pubmed/26637205 http://dx.doi.org/10.1186/s12859-015-0825-4 |