Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization

BACKGROUND: Astrocytes may play important roles in the pathogenesis of Alzheimer’s disease (AD) by clearing extracellular amyloid beta (Aβ) through endocytosis and degradation. We recently showed that metallothionein 3 (Mt3), a zinc-binding metallothionein that is enriched in the central nervous sys...

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Detalles Bibliográficos
Autores principales: Lee, Sook-Jeong, Seo, Bo-Ra, Koh, Jae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670512/
https://www.ncbi.nlm.nih.gov/pubmed/26637294
http://dx.doi.org/10.1186/s13041-015-0173-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670512/
https://www.ncbi.nlm.nih.gov/pubmed/26637294
http://dx.doi.org/10.1186/s13041-015-0173-3

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