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Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization
BACKGROUND: Astrocytes may play important roles in the pathogenesis of Alzheimer’s disease (AD) by clearing extracellular amyloid beta (Aβ) through endocytosis and degradation. We recently showed that metallothionein 3 (Mt3), a zinc-binding metallothionein that is enriched in the central nervous sys...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670512/ https://www.ncbi.nlm.nih.gov/pubmed/26637294 http://dx.doi.org/10.1186/s13041-015-0173-3 |