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Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions

INTRODUCTION: Demyelinated axons in multiple sclerosis (MS) lesions have an increased energy demand in order to maintain conduction. However, oxidative stress-induced mitochondrial dysfunction likely alters glucose metabolism and consequently impairs neuronal function in MS. Imaging and pathological...

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Detalles Bibliográficos
Autores principales: Nijland, Philip G., Molenaar, Remco J., van der Pol, Susanne M. A., van der Valk, Paul, van Noorden, Cornelis J. F., de Vries, Helga E., van Horssen, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670517/
https://www.ncbi.nlm.nih.gov/pubmed/26637184
http://dx.doi.org/10.1186/s40478-015-0261-8