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Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions
INTRODUCTION: Demyelinated axons in multiple sclerosis (MS) lesions have an increased energy demand in order to maintain conduction. However, oxidative stress-induced mitochondrial dysfunction likely alters glucose metabolism and consequently impairs neuronal function in MS. Imaging and pathological...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670517/ https://www.ncbi.nlm.nih.gov/pubmed/26637184 http://dx.doi.org/10.1186/s40478-015-0261-8 |