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NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice

BACKGROUND: Structural and functional changes of the hippocampus are correlated with psychiatric disorders and cognitive dysfunctions. Genetic deletion of heparin-binding epidermal growth factor-like growth factor (HB-EGF), which is predominantly expressed in cortex and hippocampus, also causes simi...

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Detalles Bibliográficos
Autores principales: Sasaki, Keita, Omotuyi, Olaposi Idowu, Ueda, Mutsumi, Shinohara, Kazuyuki, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670538/
https://www.ncbi.nlm.nih.gov/pubmed/26637193
http://dx.doi.org/10.1186/s13041-015-0176-0