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Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications

Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compar...

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Detalles Bibliográficos
Autores principales: Choudry, Fizzah Aziz, Frontini, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670691/
https://www.ncbi.nlm.nih.gov/pubmed/26681950
http://dx.doi.org/10.1155/2016/5797521